The dark comedy was the most-watched new series in Showtime’s history when it debuted last year. It airs Mondays at 10 p.m.

“I’m a fan of the show. I love watching these characters and how they all interact,” Facinelli said.

Edie Falco stars as Nurse Jackie Peyton, a drug addict who is both unethical on the job and in her marriage. Facinelli’s character, a young, Ivy League-educated “know-it-all,” is somewhat smitten with his co-worker.

“He’s kind of like the kid in third grade who has a crush on somebody, but it’s not being reciprocated, so he’s constantly pulling on her pigtails trying to get a reaction out of her,” he said.

Facinelli, who plays the patriarch vampire clan leader Dr. Carlisle Cullen in the “Twilight” series, returns with the third installment, “Eclipse,” out June 30. Facinelli says “Eclipse” will be more action-based and will feature the Cullens in a different light.

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